Butternut squash lasagna is a Mediterranean version of classic Italian lasagna. Tender lasagna noodles, creamy butternut squash sauce with sage, and Italian cheeses comes together in a delicious and rich autumn dish.
My high school friend, Rita sent me a recipe for Butternut Squash Lasagna many years ago, and told me I had to try it. Rita’s an excellent cook and we share recipes a lot, so if she gives it the thumbs up, it’s worth a try.
It’s a Martha Stewart recipe requiring fresh lasagna noodles. Don’t tell Martha, but I used no-boil pasta noodles!
This recipe for Butternut Squash Lasagna has browned butter and sage, and is a great vegetarian addition to your fall or Thanksgiving menus. (This post was originally published on October 28th, 2011 and has been updated to contain nutritional information. As an Amazon Affiliate, I earn commission on qualifying purchases.)
I’m not going to lie, this isn’t the quickest recipe on my site. It does require some prep work. I’ve adapted the recipe and indicated changes and where you can save time.
How to make Butternut Squash Lasagna with Sage
Preparing the Butternut Squash
The original recipe uses a whole butternut squash, which is then peeled, cubed and roasted. Many grocery stores carry pre-cubed butternut squash. You’ll need about 3 pounds prepared squash, or a whole squash that’s approximately 3 1/2 pounds. If you’re using a whole squash, peel, seed and cube the squash.
Roast the squash
Once you’ve cubed the squash, toss it with olive oil and kosher salt and pepper and roast the cubes at 425 degrees F. for about 25 minutes, or until it is tender. The time will depend on how large or small the cubes are, so test them at 20 minutes.
Prepare the lasagna filling
There are two fillings that make up the layers of this lasagna. First the cooked squash is partially mashed so that it retains some small chunks. The cooked squash is mixed with chicken broth and chopped sage leaves that are cooked in browned butter. You can mash the squash with the back of a spoon, or use your hands. You’ll want some small chunks of squash in the mixture.
The second filling is a combination of ricotta, cream, egg yolks and fresh mozzarella cut into cubes, and chicken or vegetable broth. To save time, you can also use pre-shredded mozzarella.
Martha uses fresh lasagna noodles. If you’re feeling very ambitious, you can make your own lasagna noodles, or use no-boil lasagna noodles. If you do use no-boil noodles, you’ll need to increase the amount of chicken broth by 1/2 cup.
Assembling the lasagna
Once you’ve prepared the butternut squash and ricotta fillings, you are ready to assemble.
- Start with a thin layer of ricotta mixture on the bottom of the pan.
- Add a layer of noodles. If they don’t fit perfectly, you can break them to fit.
- Spread 1/2 of the butternut and sage mixture over the noodles.
- Add another layer of noodles.
- Spread about 1 cup of ricotta mixture over noodles.
- Repeat, noodles, squash, noodles, ricotta.
- Top ricotta mixture with grated parmesan cheese.
I hope you enjoy this delicious autumn lasagna!
Are you looking for more recipes using no-boil noodles? This Three Cheese Manicotti from Christina’s Cucina looks delicious!
Butternut Squash Lasagna with Sage
Butternut squash filling
- 3 1/2 pounds butternut squash peeled, seeded and cut into 1 inch pieces
- 2 Tablespoons extra-virgin olive oil
- kosher salt and pepper
- 1 1/4 cups chicken broth (use an additional 1/2 cup if using no-cook noodles)
- 2 tablespoons unsalted butter
- 1/3 loosely packed fresh sage leaves coarsely chopped
- 1 pound whole-milk ricotta cheese
- 1/2 cup heavy cream
- 2 large eggs yolks
- 1/2 pound fresh mozzarella cheese cut into chunks (or shredded)
- 1 teaspoon Freshly grated nutmeg... I used ground
- fresh lasagna noodles or no-boil (see note above about stock)
- 4 ounces Parmesan cheese grated
Preparing the squash
- Preheat oven to 425* F. Toss squash, 2 Tablespoons oil, and 1 teaspoon salt on a baking sheet. Season with pepper. Bake until light gold and tender, 25 to 30 minutes. Let cool.
- Melt butter in a small saute pan over medium-high heat. As soon as it starts to sizzle, add sage and cook until light gold and slightly crisp at edges, 3 to 4 minutes.
- Place squash in a medium bowl and mash 1/2 with the back of a wooden spoon. (I use my hands to do this) Leave the other 1/2 of the squash in small chunks. Gently stir in sage-butter mixture and chicken or vegetable broth. Season with 1 teaspoon salt and 1/4 teaspoon white pepper.
- Reduce oven temperature to 375* F. Combine ricotta, cream, yolks, mozzarella in a medium bowl. Season with 1/2 teaspoon salt and 1/4 teaspoon white pepper and pinch of nutmeg.
- Spread 3/4 cup of ricotta mixture in a 9 cup baking dish. Top with a layer of noodles. Spread 1/2 of the butternut squash mixture over the noodles. Top with a layer of noodles. Spread 1 cup of ricotta mixture over noodles. Repeat layering once more, (noodles, squash, noodles, ricotta) Sprinkle Parmesan over ricotta mixture.
- Place baking dish on a rimmed baking sheet and cover with foil. Bake until cheese is golden and bubbling, 30 to 35 minutes. Let stand for 15 minutes before serving.
- To save time, use pre-cubed butternut squash and pre-shredded mozzarella cheese.
- To make this completely vegetarian, substitute the chicken broth for vegetable stock.
- In place of fresh noodles, you can substitute no-boil noodles. If using no-boil noodles, increase chicken or vegetable stock by 1/2 cup.
Heidy L. McCallum says
Shashi at RunninSrilankan says
Love the sage and squash combo – This lasagna is sure to be a hit!
Now that is fall in a dish! I have been roasting a lot of butternut squash lately… this dish is in my future. 🙂
Sarah Walker Caron (Sarah's Cucina Bella) says
Sounds tasty! I love that you and your friend share recipes like that.
Kristen @ A Mind Full Mom says
Cynthia, I would happily peel butternut squash to enjoy this recipe! YUM!
heather @french press says
I just love squash and sage together – I bet it makes an excellent lasagan
merry lu says
I am anxious to try this, thank you for sharing! FYI, the trick is to bake the squash BEFORE you peel it.
This looks wonderful. Can you tell me the brand of no-boil noodles you recommend? I’ve just discovered these, and what a nice step-saver!
This is a quintessential autumn recipe! The flavors are absolutely perfect together, but now I want a slice (or two) and don’t have squash to make this! (Runs to the store!)
Than you Deborah!
Toni | This Mama Style says
Wow, I would have never thought to put butternut squash with pasta. I don’t think it would go down well in my house though as my hubby & sons are the ultimate carnivores lol!
Mine is too! But it would also make a fabulous side dish during the holidays!
I can’t wait to give this a try – it sounds delicious! Thanks for the inspiration.
you’re welcome! My daughters have asked for it again while butternut is still in season!
Dan "Jay" Reyes says
I have yet to taste the Mediterranean version of the classic Italian lasagna so this is new for me! Thanks for sharing your recipe 🙂
that sounds so delicious! I’ve never tried butternut squash lasagna, what a great idea!
Oh my goodness, yum! We try to have butternut squash at least once a week when it’s fall and this looks perfect for an upcoming meal… Thank you for sharing!
Melanie williams says
Ooo yes please this is right up my street for sure, as I love butternut squash. Love the step by step instructions too x
Had to come back to say how much we loved this dish. Made it as written, and it was spot on – delicious! Will be on the menu often in the next few months, thank you!
Thanks so much Erica! We love it too!
Nancy Gianoli says
Can you use regular dry lasagna noodles? If so, do you need to cook them first?
Yes Nancy, in which case you’d want to cook them just as you would if you were making regular lasagna.
Great as a side dish with turkey or ham, or roasted pork loin!
Thank you! Glad you liked it!